Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517879 | 0.91 | KMT2A (0.62) | KMT2ALMNAPKMRAB9ASMN1; SMN2 | |
| SCHEMBL29517953 | 0.89 | KMT2A (0.60) | KMT2ALMNAPKMRAB9ASMN1; SMN2 | |
| SCHEMBL29517972 | 0.85 | KMT2A (0.56) | KMT2ALMNAPKMRAB9ASMN1; SMN2 | |
| SCHEMBL13947349 | 0.80 | RAB9A (0.65) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29517825 | 0.80 | SMN1; SMN2 (0.73) | KMT2ALMNAPKMRAB9ASMN1; SMN2 | |
| SCHEMBL19380261 | 0.79 | KDM4E (0.54) | SMN1; SMN2GSK3B | |
| SCHEMBL30129915 | 0.77 | MAPT (0.61) | KMT2ASMN1; SMN2 | |
| SCHEMBL24325692 | 0.77 | KDM4E (0.52) | GSK3B | |
| SCHEMBL19380242 | 0.77 | GSK3B (0.58) | KMT2ALMNASMN1; SMN2NPC1MEN1 | |
| SCHEMBL28607764 | 0.74 | HIF1A (0.65) | KMT2ARAB9ASMN1; SMN2NPC1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213403-B | 1,2,4-oxadiazole-5-formamide derivative and preparation method and application thereof | 贵州大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114213403-A | 1,2, 4-oxadiazole-5-formamide derivatives and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| CN-114213403-B | 1,2,4-oxadiazole-5-formamide derivative and preparation method and application thereof | 贵州大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-114213403-A | 1,2, 4-oxadiazole-5-formamide derivatives and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | disclosed |