Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PTGFR | P43088 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517953 | 0.91 | KMT2A (0.60) | KMT2APKMLMNARAB9ANPC1 | |
| SCHEMBL29517835 | 0.91 | KMT2A (0.60) | KMT2APKMLMNARAB9ANPC1 | |
| SCHEMBL29517972 | 0.87 | KMT2A (0.56) | KMT2APKMLMNARAB9ANPC1 | |
| SCHEMBL29517825 | 0.83 | SMN1; SMN2 (0.73) | KMT2APKMLMNARAB9ANPC1 | |
| SCHEMBL28607764 | 0.82 | HIF1A (0.65) | KMT2ARAB9ANPC1SMN1; SMN2GSK3B | |
| SCHEMBL28606422 | 0.80 | HIF1A (0.61) | KMT2APKMLMNARAB9ANPC1 | |
| SCHEMBL1394203 | 0.78 | RAB9A (0.74) | KMT2ALMNARAB9ANPC1MEN1 | |
| SCHEMBL483578 | 0.78 | RAB9A (0.74) | KMT2ALMNARAB9ANPC1MEN1 | |
| SCHEMBL1476766 | 0.77 | RAB9A (0.80) | KMT2ALMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29517890 | 0.77 | KMT2A (0.57) | KMT2APKMLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213403-B | 1,2,4-oxadiazole-5-formamide derivative and preparation method and application thereof | 贵州大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114213403-B | 1,2,4-oxadiazole-5-formamide derivative and preparation method and application thereof | 贵州大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-114213403-A | 1,2, 4-oxadiazole-5-formamide derivatives and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | disclosed |