Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MASP2 | O00187 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.56 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22505301 | 1.00 | ALDH1A1 (0.73) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL22500583 | 0.87 | NOTUM (0.67) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL22500581 | 0.87 | NOTUM (0.67) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL22505805 | 0.81 | F2 (0.68) | ALDH1A1MAPTNOTUMHPGDMASP2 | |
| SCHEMBL22500842 | 0.81 | F2 (0.68) | ALDH1A1MAPTNOTUMHPGDMASP2 | |
| SCHEMBL22500843 | 0.81 | F2 (0.68) | ALDH1A1MAPTNOTUMHPGDMASP2 | |
| SCHEMBL13726231 | 0.81 | MAPT (0.72) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL22500151 | 0.81 | MAPT (0.72) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL11291984 | 0.81 | MAPT (0.72) | ALDH1A1MAPTNOTUMNPC1RAB9A | |
| SCHEMBL24534874 | 0.80 | NPC1 (0.74) | ALDH1A1MAPTNOTUMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071777-A1 | COMPOSITION AND METHOD FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE | 연세대학교 산학협력단 | 2022-04-07 | — | — | WO | claimed |
| WO-2022071777-A1 | COMPOSITION AND METHOD FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE | 연세대학교 산학협력단 | 2022-04-07 | — | — | WO | disclosed |