Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.55 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518232 | 0.80 | ALDH1A1 (0.73) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL22505301 | 0.80 | ALDH1A1 (0.73) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL24534483 | 0.79 | HPGD (0.61) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL6799713 | 0.79 | POLB (0.71) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL6799710 | 0.79 | POLB (0.71) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL7658774 | 0.78 | NPC1 (0.60) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL7658770 | 0.78 | NPC1 (0.60) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL21217197 | 0.78 | SMN1; SMN2 (0.68) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL12914553 | 0.78 | SMN1; SMN2 (0.68) | NPC1HPGDRAB9ADAPK3MEN1 | |
| SCHEMBL24534666 | 0.77 | ALOX5 (0.64) | NPC1HPGDRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193041-A1 | NOVEL COMPOUND AND METHOD FOR PREVENTING OR TREATING OF RESPIRATORY DISEASES COMPRISING THE SAME AS AN ACTIVE INGREDIENT | Yonsei University, University - Industry Foundation (UIF) (KR) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193041-A1 | NOVEL COMPOUND AND METHOD FOR PREVENTING OR TREATING OF RESPIRATORY DISEASES COMPRISING THE SAME AS AN ACTIVE INGREDIENT | EPX, CFTR, MPO | NPC1 47/4885HPGD 287/4885RAB9A 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.