Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | KAT7 | O95251 | 2/20 | 0.34 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802475 | 1.00 | BRD4 (0.36) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432562 | 0.87 | TRPV4 (0.38) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432587 | 0.86 | PDE4A (0.40) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432503 | 0.81 | KAT7 (0.43) | SCN9AKAT7KAT6BKAT6AKAT5 | |
| SCHEMBL31371760 | 0.81 | KAT7 (0.38) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432685 | 0.80 | KAT7 (0.41) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432602 | 0.79 | KAT7 (0.44) | BRD4SCN9AKAT7KAT6BKAT6A | |
| SCHEMBL31432522 | 0.77 | IKBKE (0.38) | SCN9AKAT7KAT6BKAT6AKAT5 | |
| SCHEMBL31432570 | 0.77 | GAA (0.39) | BRD4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL31371751 | 0.75 | SCN9A (0.51) | SCN9AGAAMAPTARHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364672-B | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2024-09-06 | — | — | CN | disclosed |
| CN-114364672-A | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2022-04-15 | — | — | CN | disclosed |