SCHEMBL31432503

SCHEMBL31432503

COc1cc(C#N)c(F)cc1Cn1cccn1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 10/20 0.43
▸ KAT6A Q92794 10/20 0.43
▸ KAT6B Q8WYB5 8/20 0.43
▸ KAT5 Q92993 4/20 0.43
▸ KAT8 Q9H7Z6 4/20 0.43
▸ PDE4B Q07343 1/20 0.40
▸ HTR2A P28223 1/20 0.39
▸ MAPT P10636 3/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ RET P07949 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ SCN9A Q15858 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432685 0.89 KAT7 (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31432602 0.85 KAT7 (0.44) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31432562 0.84 TRPV4 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31432522 0.83 IKBKE (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31432587 0.83 PDE4A (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802475 0.81 BRD4 (0.36) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29518336 0.81 BRD4 (0.36) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31371760 0.78 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802414 0.77 KAT7 (0.45) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29490395 0.77 KAT7 (0.45) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741389-A1 KAT6 INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2026-05-13 — — EP disclosed
WO-2025007873-A1 KAT6 INHIBITOR 上海齐鲁制药研究中心有限公司 2025-01-09 — — WO disclosed
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