SCHEMBL29519178

SCHEMBL29519178

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 15/20 0.79
▸ NMUR1 Q9HB89 14/20 0.79
▸ NTSR2 O95665 1/20 0.71
▸ NTSR1 P30989 1/20 0.71
▸ OPRM1 P35372 1/20 0.67
▸ OPRD1 P41143 1/20 0.67
▸ OPRK1 P41145 1/20 0.67
▸ NPY1R P25929 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29604581 0.92 NMUR2 (0.77) NMUR2NMUR1OPRM1OPRD1OPRK1
SCHEMBL29494603 0.89 NMUR2 (0.66) NMUR2NMUR1NTSR2NTSR1NPY1R
SCHEMBL29733484 0.89 NTSR1 (0.69) NMUR2NMUR1NTSR2NTSR1OPRM1
SCHEMBL29493537 0.89 NTSR1 (0.70) NMUR2NMUR1NTSR2NTSR1OPRM1
SCHEMBL29698606 0.89 NMUR2 (0.71) NMUR2NMUR1OPRM1OPRD1OPRK1
SCHEMBL29370026 0.89 NMUR2 (0.71) NMUR2NMUR1OPRM1OPRD1OPRK1
SCHEMBL3539226 0.89 NMUR2 (0.71) NMUR2NMUR1OPRM1OPRD1OPRK1
SCHEMBL29479234 0.87 NTSR1 (0.66) NMUR2NMUR1NTSR2NTSR1OPRM1
SCHEMBL8808113 0.86 NMUR2 (0.70) NMUR2NMUR1OPRM1OPRK1
SCHEMBL8808129 0.86 NMUR2 (0.70) NMUR2NMUR1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2026506334-A — ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 2026-02-24 — — JP disclosed
WO-2026013210-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-01-15 — — WO disclosed
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US disclosed
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US disclosed
EP-4648849-A1 NMU RECEPTOR 2 AGONISTS Boehringer Ingelheim International GmbH (DE) 2025-11-19 — — EP disclosed
EP-4648849-A1 NMU RECEPTOR 2 AGONISTS Boehringer Ingelheim International GmbH (DE) 2025-11-19 — — EP disclosed
CN-120603839-A NMU receptor 2 agonists 勃林格殷格翰国际有限公司 2025-09-05 — — CN disclosed
US-20240279278-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-08-22 — — US disclosed
US-20240279278-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-08-22 — — US disclosed
WO-2024149820-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-07-18 — — WO disclosed
WO-2024149820-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-07-18 — — WO disclosed
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-05-23 — — US disclosed
WO-2022186782-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-09-09 — — WO disclosed
US-20220213461-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-07 — — US disclosed
CN-106459160-B ASX-specific protein ligases 南洋理工大学 2022-03-29 — — CN disclosed
EP-3966321-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF Nanyang Technological University (SG) 2022-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015393-A1 NOVEL NMU RECEPTOR 2 AGONISTS NMUR2, NMUR1, GPR18 NMUR2 1/4885NMUR1 2/4885NTSR2 41/4885
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE ANPEP, DNPEP, ASNS NMUR2 1038/4885NMUR1 890/4885NTSR2 330/4885
US-20240279278-A1 NMU RECEPTOR 2 AGONISTS NMUR2, NMUR1, NMBR NMUR2 1/4885NMUR1 2/4885NTSR2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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