SCHEMBL29519556

SCHEMBL29519556

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 6/20 0.49
▸ NPY4R P50391 9/20 0.48
▸ NPY1R P25929 6/20 0.48
▸ NPY2R P49146 4/20 0.48
▸ NPY5R Q15761 4/20 0.48
▸ GLP1R P43220 1/20 0.46
▸ SCTR P47872 1/20 0.46
▸ KEAP1 Q14145 1/20 0.45
▸ VIPR1 P32241 1/20 0.45
▸ VIPR2 P41587 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526513 0.88 GLP1R (0.57) KISS1RNPY2RGLP1RSCTRVIPR1
SCHEMBL30676227 0.87 NPY4R (0.46) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29684563 0.87 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL17887897 0.86 NPY4R (0.61) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL17887995 0.86 NPY4R (0.61) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL31627888 0.86 GLP1R (0.53) GLP1RSCTRKEAP1VIPR2
SCHEMBL31516403 0.85 GLP1R (0.49) GLP1RSCTRKEAP1VIPR1VIPR2
SCHEMBL29519563 0.85 OPRM1 (0.50) KISS1RNPY4RNPY1RNPY2R
SCHEMBL31474484 0.85 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL29808185 0.85 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709750-A1 BISPECIFIC ANTI-PSEUDOMONAS ANTIBODIES WITH MODIFIED FC REGIONS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2026-03-18 — — EP disclosed
WO-2024231440-A1 BISPECIFIC ANTI-PSEUDOMONAS ANTIBODIES WITH MODIFIED FC REGIONS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-11-14 — — WO disclosed
US-20240124612-A1 MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES MEDIMMUNE LLC 2024-04-18 — — US disclosed
US-11767369-B2 Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties MEDIMMUNE, LLC (US) 2023-09-26 — — US disclosed
CN-106413750-B Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties 免疫医疗有限责任公司 2022-04-29 — — CN disclosed
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