Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 8/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679754 | 0.95 | OPRM1 (0.54) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL29450325 | 0.87 | OPRM1 (0.53) | OPRM1OPRD1KISS1ROPRK1 | |
| SCHEMBL30390358 | 0.86 | CD274 (0.41) | OPRM1OPRD1BACE1 | |
| SCHEMBL31020880 | 0.86 | NPY1R (0.49) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL31275672 | 0.86 | KISS1R (0.47) | OPRM1OPRD1KISS1RNPY1RNPY2R | |
| SCHEMBL31412207 | 0.86 | OPRD1 (0.46) | OPRD1KISS1RBACE1SLC6A2BACE2 | |
| SCHEMBL31307241 | 0.85 | BACE1 (0.57) | BACE1BACE2 | |
| SCHEMBL29519556 | 0.85 | KISS1R (0.49) | KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30435333 | 0.85 | OPRD1 (0.52) | OPRM1OPRD1KISS1RBACE1BACE2 | |
| SCHEMBL31020881 | 0.84 | NPY4R (0.49) | OPRD1KISS1RNPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124612-A1 | MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES | MEDIMMUNE LLC | 2024-04-18 | — | — | US | disclosed |
| US-11767369-B2 | Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties | MEDIMMUNE, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-106413750-B | Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties | 免疫医疗有限责任公司 | 2022-04-29 | — | — | CN | disclosed |