Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSH | P09668 | 1/20 | 0.52 |
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.49 |
| ▸ | CALCR | P30988 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31096802 | 0.92 | C5AR1 (0.53) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30547344 | 0.92 | EPHA2 (0.55) | C5AR1F2CTSLCTSSCTSK | |
| SCHEMBL30208250 | 0.88 | EPHA2 (0.56) | C5AR1MC4RF2CTSLCTSS | |
| SCHEMBL30948380 | 0.88 | APLNR (0.52) | C5AR1F2CTSLCTSSCTSK | |
| SCHEMBL29641118 | 0.88 | C5AR1 (0.60) | C5AR1MC4RF2APLNREPHA2 | |
| SCHEMBL29641093 | 0.87 | C5AR1 (0.64) | C5AR1MC4RF2APLNROPRM1 | |
| SCHEMBL30997477 | 0.87 | F2 (0.52) | C5AR1F2CTSLCTSSCTSK | |
| SCHEMBL30255096 | 0.86 | NMUR2 (0.57) | C5AR1MC4RF2CTSLCTSS | |
| SCHEMBL30811617 | 0.86 | C5AR1 (0.57) | C5AR1APLNREPHA2NTSR2NTSR1 | |
| SCHEMBL32664435 | 0.86 | NTSR2 (0.58) | NTSR2NTSR1SORT1OPRM1NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124612-A1 | MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES | MEDIMMUNE LLC | 2024-04-18 | — | — | US | disclosed |
| US-11767369-B2 | Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties | MEDIMMUNE, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-106413750-B | Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties | 免疫医疗有限责任公司 | 2022-04-29 | — | — | CN | disclosed |