Golgicide A

Golgicide A

SCHEMBL29519829

Fc1cc(F)c2c(c1)[C@H]1C=CC[C@H]1[C@@H](c1cccnc1)N2

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.45
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
KDM4E B2RXH2 5/20 0.45
ALDH1A1 P00352 4/20 0.45
GAA P10253 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
MCL1 Q07820 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTPN1 P18031 1/20 0.43
POLB P06746 4/20 0.39
PKM P14618 1/20 0.39
RECQL P46063 1/20 0.39
PTPN7 P35236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Golgicide A SCHEMBL29431758 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL29374617 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL29893179 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL17167481 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL15678653 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL29384501 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
Golgicide A SCHEMBL8075106 1.00 MAPT (0.45) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL7899991 0.77 CHRNB2 (0.35) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL16168697 0.74 MAPT (0.54) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL10022355 0.72 MAPT (0.52) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071720-A RNA single base editing system based on pseudo uridine modification 北京大学 2026-05-22 CN disclosed
CN-122012509-A Aptamer, tRNA, reagent, kit and tRNA detection method for recognizing tRNA 常州新一产生命科技有限公司 2026-05-12 CN disclosed
CN-121574335-A Photo-curing resin, high-toughness adhesive product and preparation method thereof 万华化学集团股份有限公司 2026-02-27 CN disclosed
US-20250339559-A1 BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) THE BROAD INSTITUTE, INC. (US) 2025-11-06 US disclosed
US-20250027114-A1 CAS9 VARIANTS HAVING NON-CANONICAL PAM SPECIFICITIES AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2025-01-23 US disclosed
CN-118028443-A Method for detecting isopentenyl adenosine modification on RNA 华中农业大学 2024-05-14 CN disclosed
US-20240018517-A1 MODULATING HEMATAOPOIESIS AND MYLEOID CELL PRODUCTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-01-18 US disclosed
US-20230314565-A1 RADAR SIGNAL PROCESSING METHOD WITH CLUTTER SUPPRESSION CALIBRATION FUNCTION AND RADAR SENSOR APPLYING THE SAME KOREA ELECTRONICS TECHNOLOGY INSTITUTE (KR) 2023-10-05 US disclosed
EP-4066938-A1 CATALYST FOR THE HYDROGENATION OF CO2 TO METHANE AT LOW TEMPERATURES Consejo Superior de Investigaciones Cientificas (ES) 2022-10-05 EP disclosed
WO-2022202607-A1 SOLID OR GEL ELECTROLYTE, CURED-TYPE COMPOSITION FOR SOLID OR GEL ELECTROLYTE, AND LITHIUM ION SECONDARY BATTERY 東亞合成株式会社 2022-09-29 WO disclosed
CN-114457039-A Genetically modified anti-third party central memory T cells and their use in immunotherapy 耶达研究及发展有限公司 2022-05-10 CN disclosed
US-11306049-B2 Process using catalytic composition for the conversion of syngas to higher alcohols TOTAL SE (FR) 2022-04-19 US disclosed
CN-114222760-A IL1RAP binding proteins 葛兰素史密斯克莱知识产权发展有限公司 2022-03-22 CN disclosed