Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NME2 | P22392 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519449 | 0.86 | NPC1 (0.62) | NME2MEN1KMT2A | |
| SCHEMBL29519914 | 0.83 | MEN1 (0.58) | NME2MEN1KMT2ABLM | |
| SCHEMBL29519693 | 0.76 | RAB9A (0.67) | NME2MEN1KMT2A | |
| SCHEMBL29519827 | 0.76 | RAB9A (0.66) | NME2MEN1KMT2A | |
| SCHEMBL29519694 | 0.76 | MEN1 (0.66) | NME2MEN1KMT2ABLM | |
| SCHEMBL29520052 | 0.75 | MEN1 (0.66) | NME2MEN1KMT2A | |
| SCHEMBL29519683 | 0.75 | MEN1 (0.60) | NME2MEN1KMT2ABLM | |
| SCHEMBL29520018 | 0.75 | NME2 (0.64) | NME2MEN1KMT2ABLM | |
| SCHEMBL29519532 | 0.75 | RAB9A (0.68) | MEN1KMT2A | |
| SCHEMBL11081325 | 0.73 | KMT2A (0.72) | NME2MEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249733-B | Isaindigotone derivative and application thereof in preparation of antitumor drugs | 兰州大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114249733-A | Isaindigotone derivative and application thereof in preparation of antitumor drugs | 兰州大学 | 2022-03-29 | — | — | CN | disclosed |