SCHEMBL29520101

SCHEMBL29520101

CCCC[C@H](NC(=O)[C@H](N)CC(C)C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 5/20 0.60
ERAP2 Q6P179 4/20 0.60
CCKAR P32238 1/20 0.59
CCKBR P32239 1/20 0.59
OPRD1 P41143 1/20 0.59
IL1RN P18510 1/20 0.59
ERAP1 Q9NZ08 2/20 0.58
ANPEP P15144 1/20 0.58
NPY1R P25929 3/20 0.57
NPY2R P49146 3/20 0.57
NPY4R P50391 3/20 0.57
GHSR Q92847 1/20 0.57
ACE P12821 1/20 0.56
KISS1R Q969F8 1/20 0.56
LNPEP Q9UIQ6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519671 0.96 ECE1 (0.65) ECE1ERAP2CCKARCCKBROPRD1
SCHEMBL30050840 0.93 ECE1 (0.68) ECE1ERAP2IL1RNERAP1ANPEP
SCHEMBL29381352 0.93 ECE1 (0.68) ECE1ERAP2IL1RNERAP1ANPEP
SCHEMBL29519590 0.89 ERAP2 (0.55) ECE1ERAP2IL1RNERAP1ANPEP
SCHEMBL30051190 0.89 ECE1 (0.74) ECE1ERAP2IL1RNERAP1ANPEP
SCHEMBL30044908 0.89 KISS1R (0.61) ERAP2IL1RNKISS1R
SCHEMBL30123045 0.88 ECE1 (0.62) ECE1ERAP2IL1RNERAP1ANPEP
SCHEMBL30845362 0.88 ERAP2 (0.71) ECE1ERAP2OPRD1IL1RNERAP1
SCHEMBL30368556 0.88 ACE (0.64) ECE1ERAP2ERAP1GHSRACE
SCHEMBL14940856 0.87 ECE1 (0.77) ECE1ERAP2ERAP1ANPEPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US claimed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 US claimed
EP-4211146-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS Bar Ilan University (IL) 2023-07-19 EP claimed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 US disclosed
EP-4211146-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS Bar Ilan University (IL) 2023-07-19 EP disclosed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 ECE1 2453/4885ERAP2 527/4885CCKAR 322/4885
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS IAPP, QPCTL, DNPEP ECE1 2848/4885ERAP2 480/4885CCKAR 1851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.