Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | TEC | P42680 | 1/20 | 0.42 |
| ▸ | TXK | P42681 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754856 | 1.00 | BTK (0.45) | BTKKCNH2ABCB11EGFRERBB2 | |
| SCHEMBL17770645 | 0.90 | BTK (0.39) | BTKKCNH2ABCB11EGFRERBB2 | |
| SCHEMBL25981351 | 0.85 | LIPE (0.38) | BTKKCNH2ABCB11EGFRERBB2 | |
| SCHEMBL31473998 | 0.83 | LIPE (0.36) | BTK | |
| SCHEMBL27003891 | 0.83 | LIPE (0.39) | KCNH2 | |
| SCHEMBL29606402 | 0.81 | BTK (0.45) | BTK | |
| SCHEMBL14646795 | 0.81 | BTK (0.45) | BTK | |
| SCHEMBL30636787 | 0.79 | BTK (0.49) | BTKKCNH2ABCB11EGFRERBB2 | |
| SCHEMBL29118527 | 0.79 | BTK (0.49) | BTKKCNH2ABCB11EGFRERBB2 | |
| SCHEMBL17780098 | 0.79 | BTK (0.50) | BTKKCNH2ABCB11EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172056-B | Aminopyrimidine derivatives | 诺华股份有限公司 | 2022-04-19 | — | — | CN | disclosed |