Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003891 | 0.84 | LIPE (0.39) | LIPENPC1HDAC1LMNANTRK1 | |
| SCHEMBL16754856 | 0.83 | BTK (0.45) | BTK | |
| SCHEMBL29520132 | 0.83 | BTK (0.45) | BTK | |
| SCHEMBL14646795 | 0.82 | BTK (0.45) | LIPENPC1HDAC1BTKNTRK1 | |
| SCHEMBL29606402 | 0.82 | BTK (0.45) | LIPENPC1HDAC1BTKNTRK1 | |
| SCHEMBL31474221 | 0.78 | LIPE (0.32) | LIPEALDH1A1MAPT | |
| SCHEMBL31474008 | 0.78 | NPC1 (0.33) | LIPENPC1ALDH1A1 | |
| SCHEMBL31474202 | 0.78 | LIPE (0.34) | LIPECXCR2 | |
| SCHEMBL31474067 | 0.78 | LIPE (0.34) | LIPEALDH1A1MAPTCXCR2 | |
| SCHEMBL31474190 | 0.77 | BTK (0.34) | LIPENPC1ALDH1A1MAPTBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |