SCHEMBL29520290

SCHEMBL29520290

CC(C)(C)C1=Nc2ccccc2C(=C2CCCCC2)C(c2ccccc2)=N1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
ACHE P22303 1/20 0.32
GAA P10253 2/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520777 0.99 IDO1 (0.39) IDO1ACHEGAALMNAMAPT
SCHEMBL29520800 0.91 RAB9A (0.32) IDO1ACHEMAPT
SCHEMBL29520487 0.72 IDO1 (0.41) IDO1GAALMNAMAPTHTT
SCHEMBL29520737 0.70 IDO1 (0.40) IDO1GAALMNAMAPTHTT
SCHEMBL29520695 0.70 MAPT (0.43) IDO1GAALMNAMAPTHTT
SCHEMBL29520723 0.69 IDO1 (0.39) IDO1GAALMNAMAPTHTT
SCHEMBL29520576 0.64 IDO1 (0.31) IDO1
SCHEMBL29520721 0.64 MEN1 (0.33) IDO1LMNAMAPTHTTNPSR1
SCHEMBL18977949 0.62 IDO1 (0.69) IDO1GAALMNAMAPTHTT
SCHEMBL30816758 0.62 IDO1 (0.69) IDO1GAALMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174901-B Synthesis method and anticancer activity of 1, 3-benzodiazepine compound 河南师范大学 2022-02-08 CN disclosed