Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520290 | 0.99 | IDO1 (0.38) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL29520800 | 0.90 | RAB9A (0.32) | IDO1MAPTACHE | |
| SCHEMBL29520487 | 0.73 | IDO1 (0.41) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL29520695 | 0.71 | MAPT (0.43) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL29520737 | 0.71 | IDO1 (0.40) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL29520723 | 0.70 | IDO1 (0.39) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL29520721 | 0.65 | MEN1 (0.33) | IDO1LMNAMAPTHTTNPSR1 | |
| SCHEMBL29520739 | 0.64 | CNR1 (0.34) | IDO1 | |
| SCHEMBL18977949 | 0.62 | IDO1 (0.69) | IDO1GAALMNAMAPTHTT | |
| SCHEMBL30816758 | 0.62 | IDO1 (0.69) | IDO1GAALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | CLEMSON UNIVERSITY | 2025-05-15 | — | — | US | disclosed |
| CN-114805171-B | N-aryl indole compound and synthesis method thereof | 河南师范大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115353514-B | Fluoro-pyridopyrimidinone compounds and synthesis method thereof | 河南师范大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113754584-B | Synthesis method and anticancer activity of 4-amino dihydroquinolinone compound | 河南师范大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115353514-A | Fluoro-pyridopyrimidone compound and synthetic method thereof | 河南师范大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-115028657-A | Preparation method and product of 2-substituted indole spiro-compound | 中国科学院上海药物研究所 | 2022-09-09 | — | — | CN | disclosed |
| CN-114805171-A | N-aryl indole compound and synthetic method thereof | 河南师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113603679-B | Synthesis method and anticancer activity of 2-hydroxysuccinimide substituted indolone compound | 河南师范大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113185523-B | Synthetic method of 3-indolone [ spiro ] -3H-indole compound | 河南师范大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-112174901-B | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | SERPINB1, NAMPT, NIT2 | IDO1 2892/4885GAA 189/4885LMNA 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.