Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520490 | 0.82 | KDM4E (0.31) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29520737 | 0.81 | IDO1 (0.40) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29520721 | 0.80 | MEN1 (0.33) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL29520739 | 0.78 | CNR1 (0.34) | KDM4EALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL29520292 | 0.76 | CNR1 (0.35) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL29520584 | 0.76 | MAPT (0.38) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29520620 | 0.76 | CNR1 (0.38) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29520639 | 0.74 | MAPT (0.38) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL29409248 | 0.70 | NPC1 (0.36) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29520723 | 0.69 | IDO1 (0.39) | MAPTKMT2AMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174901-B | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2022-02-08 | — | — | CN | disclosed |