Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520737 | 0.87 | IDO1 (0.40) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29520721 | 0.86 | MEN1 (0.33) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL28500399 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29520739 | 0.85 | CNR1 (0.34) | KDM4EALDH1A1HSP90AA1HSP90AB1NPC1 | |
| SCHEMBL29520639 | 0.80 | MAPT (0.38) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL29520490 | 0.78 | KDM4E (0.31) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29520292 | 0.78 | CNR1 (0.35) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL29520620 | 0.77 | CNR1 (0.38) | MAPTKMT2AABL1HSP90AA1HSP90AB1 | |
| SCHEMBL29520342 | 0.76 | MAPT (0.40) | MAPTMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29409248 | 0.74 | NPC1 (0.36) | MAPTMEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174901-B | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2022-02-08 | — | — | CN | disclosed |