Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520721 | 0.83 | MEN1 (0.33) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL29520342 | 0.82 | MAPT (0.40) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL29520737 | 0.82 | IDO1 (0.40) | KDM4EMEN1APAF1ALDH1A1LMNA | |
| SCHEMBL29520292 | 0.80 | CNR1 (0.35) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL29520739 | 0.80 | CNR1 (0.34) | KDM4EALDH1A1HSP90AA1HSP90AB1TSHR | |
| SCHEMBL29520584 | 0.78 | MAPT (0.38) | KDM4EMEN1ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL29520620 | 0.77 | CNR1 (0.38) | HSP90AA1HSP90AB1MAPTKMT2ANPC1 | |
| SCHEMBL29520639 | 0.75 | MAPT (0.38) | MEN1LMNAMAPTKMT2ANPC1 | |
| SCHEMBL29409248 | 0.74 | NPC1 (0.36) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL29520545 | 0.73 | MAPT (0.42) | KDM4EMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174901-B | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2022-02-08 | — | — | CN | disclosed |