Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430284 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL26424955 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL26111320 | 0.82 | L3MBTL1 (0.40) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL29697807 | 0.82 | L3MBTL1 (0.40) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL5122957 | 0.81 | CHRNB4 (0.51) | CHRNB4CHRNA3ALDH1A1HTTLMNA | |
| SCHEMBL13681596 | 0.81 | CHRNB4 (0.51) | CHRNB4CHRNA3ALDH1A1HTTLMNA | |
| SCHEMBL2791701 | 0.81 | CHRNB4 (0.51) | CHRNB4CHRNA3ALDH1A1HTTLMNA | |
| SCHEMBL693333 | 0.81 | HTT (0.43) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL30230795 | 0.80 | ALDH1A1 (0.48) | CHRNB4CHRNA3ALDH1A1HTTLMNA | |
| SCHEMBL2792121 | 0.80 | CHRNB4 (0.47) | CHRNB4CHRNA3ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |