Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037818 | 1.00 | MEN1 (0.48) | MEN1KMT2AGRM5PARP10PARP1 | |
| SCHEMBL2205282 | 0.94 | MEN1 (0.48) | MEN1KMT2AGRM5PARP10PARP1 | |
| SCHEMBL30707511 | 0.86 | TDP1 (0.43) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL30882012 | 0.82 | PARP10 (0.53) | MEN1KMT2AGRM5PARP10PARP1 | |
| SCHEMBL4715588 | 0.82 | PARP10 (0.53) | MEN1KMT2AGRM5PARP10PARP1 | |
| SCHEMBL29581365 | 0.81 | ALDH1A1 (0.57) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL2205220 | 0.81 | ALDH1A1 (0.57) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL31510285 | 0.80 | PARP10 (0.40) | MEN1KMT2APARP10PARP1PARP11 | |
| SCHEMBL6113951 | 0.80 | TDP1 (0.43) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL7000772 | 0.80 | TDP1 (0.44) | MEN1KMT2AKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605392-A1 | METHODS FOR TREATING CANCER | Antares Therapeutics, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024086809-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-116456985-A | Pyrimidine and pyridine derivatives as HPK1 modulators and methods of use thereof | 深圳市原力生命科学有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |