Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.40 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205282 | 0.85 | MEN1 (0.48) | PARP10PARP1PARP11KDM4EMEN1 | |
| SCHEMBL28090202 | 0.82 | PDK1 (0.40) | MEN1KMT2APDK1XDHMAPT | |
| SCHEMBL29037818 | 0.80 | MEN1 (0.48) | PARP10PARP1PARP11KDM4EMEN1 | |
| SCHEMBL11518151 | 0.80 | MAPT (0.54) | MEN1KMT2APDK1XDHALDH1A1 | |
| SCHEMBL29520449 | 0.80 | MEN1 (0.48) | PARP10PARP1PARP11KDM4EMEN1 | |
| SCHEMBL18875036 | 0.78 | PARP10 (0.50) | PARP10PARP1PARP11KDM4EMEN1 | |
| SCHEMBL17064696 | 0.75 | PARP10 (0.50) | PARP10PARP1PARP11KDM4EALDH1A1 | |
| SCHEMBL31510260 | 0.75 | KDM4E (0.45) | PARP10PARP1PARP11KDM4EALDH1A1 | |
| SCHEMBL28899149 | 0.75 | ALDH1A1 (0.66) | PARP10PARP1PARP11KDM4EALDH1A1 | |
| SCHEMBL27087781 | 0.75 | KDM4E (0.45) | PARP10PARP1PARP11KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051129-A1 | ARYL HETEROCYCLIC SLC7A11 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119552124-A | Aryl heterocycle SLC7A11 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2025-03-04 | — | — | CN | disclosed |