SCHEMBL29520503

SCHEMBL29520503

Nc1ccccc1-c1cc(-c2ccccc2N)cc(-c2ccccc2N)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.70
HSD17B10 Q99714 2/20 0.70
L3MBTL1 Q9Y468 1/20 0.67
SMN1; SMN2 Q16637 2/20 0.50
ALOX15 P16050 2/20 0.50
CYP3A4 P08684 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
DHFR P00374 1/20 0.46
ADORA3 P0DMS8 1/20 0.44
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 2/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
IDO1 P14902 4/20 0.40
ATAD2 Q6PL18 1/20 0.39
ADORA2A P29274 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671941 1.00 ALDH1A1 (0.70) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL30913008 0.90 ALDH1A1 (0.73) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL29210837 0.90 ALDH1A1 (0.73) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL5162068 0.89 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL29568495 0.88 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL6480845 0.85 ALDH1A1 (0.83) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL25012067 0.84 ALDH1A1 (0.64) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL11757533 0.83 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL16616587 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15
SCHEMBL400327 0.83 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479071-B Polyimide nano particle, preparation method and application thereof 中国石油化工股份有限公司 2024-11-29 CN claimed
CN-118558364-A Polyfluoroalkyl modified COFs supported nano palladium catalyst and preparation method and application thereof 中南大学 2024-08-30 CN claimed
CN-115582027-B Preparation method of covalent organic framework organic solvent nanofiltration membrane modified by alkyl chains with different lengths 天津工业大学 2024-07-19 CN claimed
CN-117186481-A Polyphenol hydroxyl COFs aerogel rich in hydrogen bond donor, and preparation method and application thereof 中南大学 2023-12-08 CN claimed
CN-117143305-A NH (NH) 2 -COFs@ZnS photocatalytic material and preparation method and application thereof 中南大学 2023-12-01 CN claimed
CN-117101617-A Bonding type imine three-component spherical COF-based stationary phase and preparation method and application thereof 华南师大(清远)科技创新研究院有限公司 2023-11-24 CN claimed
CN-116925372-A nanocarbon@COFs hybrid material with thienyl core-shell structure and preparation method and application thereof 中南大学 2023-10-24 CN claimed
CN-114713286-B Ti-MOFs@COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2023-06-20 CN claimed
CN-116212661-A Covalent organic framework organic solvent nanofiltration membrane with odd-even effect functionalization and preparation method thereof 天津工业大学 2023-06-06 CN claimed
CN-115582027-A Preparation method of covalent organic framework organic solvent nanofiltration membrane modified by alkyl chains with different lengths 天津工业大学 2023-01-10 CN claimed
CN-112080484-B Immobilized enzyme based on magnetic COFs, synthetic method and application of immobilized enzyme in preparation of biodiesel 四川大学 2023-01-03 CN claimed
CN-114713286-A Ti-MOFs @ COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2022-07-08 CN claimed
CN-114479071-A Polyimide nano particle, preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-111921387-B Preparation method of polydopamine modified imidazolyl nanoparticle composite nanofiltration membrane 浙江工业大学 2022-03-29 CN claimed
CN-114479071-B Polyimide nano particle, preparation method and application thereof 中国石油化工股份有限公司 2024-11-29 CN disclosed
CN-118892751-A Method for preparing covalent organic framework membrane by MOF gel induction and application of covalent organic framework membrane in aromatic hydrocarbon separation 湖南大学 2024-11-05 CN disclosed
CN-118558364-A Polyfluoroalkyl modified COFs supported nano palladium catalyst and preparation method and application thereof 中南大学 2024-08-30 CN disclosed
CN-114479071-A Polyimide nano particle, preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed
CN-111921387-B Preparation method of polydopamine modified imidazolyl nanoparticle composite nanofiltration membrane 浙江工业大学 2022-03-29 CN disclosed
WO-2022054552-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER 東レ株式会社 2022-03-17 WO disclosed