Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 10/20 | 0.44 |
| ▸ | WEE1 | P30291 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037854 | 0.80 | EGFR (0.55) | PKMYT1PAK1TNIKALKINSR | |
| SCHEMBL29520433 | 0.80 | WEE1 (0.52) | PAK1WEE1SLC2A1ALKINSR | |
| SCHEMBL29037832 | 0.79 | EGFR (0.51) | PKMYT1PAK1TNIKSLC2A1ALK | |
| SCHEMBL29520379 | 0.78 | PAK1 (0.42) | PKMYT1PAK1TNIKEGFR | |
| SCHEMBL29520363 | 0.78 | PAK1 (0.42) | PKMYT1PAK1TNIKEGFR | |
| SCHEMBL29037708 | 0.78 | EGFR (0.59) | PKMYT1PAK1TNIKALKINSR | |
| SCHEMBL29520343 | 0.76 | PAK1 (0.45) | PKMYT1PAK1TNIKSLC2A1EGFR | |
| SCHEMBL29520330 | 0.75 | MAP4K1 (0.59) | ALKMET | |
| SCHEMBL29037729 | 0.75 | MAP4K1 (0.59) | ALKMET | |
| SCHEMBL29037768 | 0.74 | MAPK8 (0.51) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063140-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AS HPK1 MODULATOR AND METHODS USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2022-03-31 | — | — | WO | disclosed |