Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | NPR3 | P17342 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470108 | 0.80 | ADORA2A (0.43) | MEN1KMT2AMAPTNPR3ADORA2A | |
| SCHEMBL6695129 | 0.78 | KDM4E (0.49) | MAPTEGFRITKKDM4E | |
| SCHEMBL30679678 | 0.78 | CA9 (0.59) | — | |
| SCHEMBL16983519 | 0.78 | CA9 (0.59) | — | |
| SCHEMBL13326025 | 0.78 | ADORA2A (0.48) | MEN1KMT2AADORA2AADORA1STK17B | |
| SCHEMBL2955788 | 0.77 | ADORA2A (0.43) | ADORA2AADORA1 | |
| SCHEMBL31478285 | 0.74 | HDAC4 (0.43) | MAPTKDM4EGLAL3MBTL1ADORA2A | |
| SCHEMBL23345470 | 0.74 | POLB (0.60) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL31681549 | 0.73 | STK17B (0.46) | MEN1KMT2AEGFRITKADORA2A | |
| SCHEMBL17576107 | 0.72 | NPC1 (0.51) | MEN1KMT2AMAPTNPR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749940-B2 | Facilitated forward chemical genetics using tagged triazine library | NEW YORK UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-20050019831-A1 | Facilitated forward chemical genetics using tagged triazine library | NEW YORK UNIVERSITY (US) | 2005-01-27 | — | — | US | disclosed |
| WO-2004099106-A2 | FACILITATED FORWARD CHEMICAL GENETICS USING TAGGED TRIAZINE LIBRARY | NEW YORK UNIVERSITY (US) | 2004-11-18 | — | — | WO | disclosed |