Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955788 | 0.79 | ADORA2A (0.43) | SMN1; SMN2 | |
| SCHEMBL2952133 | 0.78 | ENO1 (0.44) | KDM4EMAPTEGFRITK | |
| SCHEMBL2124035 | 0.77 | BRD4 (0.46) | KDM4ELMNAHPGDEGFRITK | |
| SCHEMBL13326025 | 0.77 | ADORA2A (0.48) | GAA | |
| SCHEMBL21113585 | 0.76 | SMN1; SMN2 (0.72) | LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4522396 | 0.76 | SYK (0.56) | LMNAMAPTEGFR | |
| SCHEMBL25028453 | 0.75 | KMT2A (0.60) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18470108 | 0.74 | ADORA2A (0.43) | MAPT | |
| SCHEMBL7015093 | 0.74 | NFKB1 (0.54) | KDM4ELMNAGAASCN9ASMN1; SMN2 | |
| SCHEMBL2123644 | 0.74 | BCHE (0.41) | KDM4EMAPTEGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099106-A2 | FACILITATED FORWARD CHEMICAL GENETICS USING TAGGED TRIAZINE LIBRARY | NEW YORK UNIVERSITY (US) | 2004-11-18 | — | — | WO | disclosed |