SCHEMBL31478285

SCHEMBL31478285

Cc1nnc(-c2ccc(CC(=O)NCCOCCOCCOCCOCCNC(=O)OC(C)(C)C)cc2)nn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
GBA1 P04062 1/20 0.43
BRD4 O60885 1/20 0.43
BRD2 P25440 1/20 0.43
BRD3 Q15059 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SUCNR1 Q9BXA5 2/20 0.41
BCHE P06276 3/20 0.40
CNR2 P34972 3/20 0.40
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
IDO1 P14902 1/20 0.39
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22109240 0.84 KDM4E (0.44) HDAC4HDAC6KDM4EGLAL3MBTL1
SCHEMBL23659156 0.83 HDAC4 (0.44) HDAC4HDAC6BRD4BRD2BRD3
SCHEMBL24115336 0.82 HDAC4 (0.43) HDAC4HDAC6KDM4EGLAL3MBTL1
SCHEMBL24531597 0.81 L3MBTL1 (0.42) HDAC4HDAC6KDM4EGLAL3MBTL1
SCHEMBL31478321 0.81 CRBN (0.33) HDAC4HDAC6GBA1BRD4BRD2
SCHEMBL15322811 0.79 NAMPT (0.50) HDAC6BRD4L3MBTL1MAPTTDP1
SCHEMBL31041096 0.77 CA1 (0.38) GBA1BRD4BRD2BRD3SUCNR1
SCHEMBL25135280 0.77 RAB9A (0.49) HDAC4HDAC6KDM4EGLAL3MBTL1
SCHEMBL18237012 0.77 CA1 (0.51) GBA1BRD4BRD2BRD3SUCNR1
SCHEMBL29383217 0.77 CA1 (0.51) GBA1BRD4BRD2BRD3SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025083071-A2 ANTIBODY-DRUG CONJUGATES Hummingbird Bioscience Pte. Ltd. (SG) 2025-04-24 WO disclosed
WO-2025083069-A1 HER2-BINDING MOLECULES Hummingbird Bioscience Pte. Ltd. (SG) 2025-04-24 WO disclosed