Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.63 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.63 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.63 |
| ▸ | AXL | P30530 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726707 | 0.87 | MAOA (0.95) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL6797870 | 0.87 | MAOA (0.95) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL30469285 | 0.87 | MAOA (0.95) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL12076750 | 0.87 | MKNK1 (0.57) | MAOAMEN1MKNK1MKNK2CYP11B1 | |
| SCHEMBL558114 | 0.85 | DYRK1B (0.54) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL5533122 | 0.85 | MKNK1 (0.55) | MAOAMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL22664854 | 0.85 | MAOA (0.90) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL13447740 | 0.85 | MAOA (0.90) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL173011 | 0.85 | MAOA (1.00) | MAOAMEN1MKNK1MKNK2PSIP1 | |
| SCHEMBL29625959 | 0.85 | MAOA (1.00) | MAOAMEN1MKNK1MKNK2PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776335-B | Amine derivative of pyrene, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2022-03-18 | — | — | CN | disclosed |