SCHEMBL295220

SCHEMBL295220

OC[C@H]1O[C@H](O[C@@H]2[C@@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)O[C@H](CO)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 1/20 0.57
▸ LGALS3 P17931 1/20 0.57
▸ LGALS4 P56470 1/20 0.57
▸ MEN1 O00255 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ AMY2A P04746 2/20 0.51
▸ ENGASE Q8NFI3 1/20 0.50
▸ CD209 Q9NNX6 1/20 0.50
▸ FGF1 P05230 1/20 0.47
▸ FGF2 P09038 1/20 0.47
▸ VEGFA P15692 1/20 0.47
▸ HPSE Q9Y251 1/20 0.47
▸ TYR P14679 2/20 0.47
▸ AMY1A P0DUB6 1/20 0.47
▸ TSHR P16473 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ GJA1 P17302 1/20 0.46
▸ GJB2 P29033 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31614391 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31701579 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31700326 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31700334 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31614389 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL295024 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL3149886 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31614393 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL21243223 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A
SCHEMBL31700630 1.00 LGALS8 (0.57) LGALS8LGALS3LGALS4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040121431-A1 used for formation of cyclotetrasaccharide from a saccharide with a glucose polymerization degree of 3 or higher; genetic engineering KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2004-06-24 — — US claimed
EP-1335020-A1 POLYPEPTIDES HAVING ALPHA-ISOMALTOSYL TRANSFERASE ACTIVITY Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-08-13 — — EP claimed
JP-63046201-A — — None — — JP disclosed
CN-113549606-B Alpha-amylase variants with altered properties 诺维信公司 2024-07-16 — — CN disclosed
US-20240218340-A1 Enzyme Variants and Polynucleotides Encoding Same NOVOZYMES A/S (DK) 2024-07-04 — — US disclosed
US-20240093170-A1 Enzyme Variants and Polynucleotides Encoding the Same NOVOZYMES A/S (DK) 2024-03-21 — — US disclosed
US-11859221-B2 Enzyme variants and polynucleotides encoding the same NOVOZYMES A/S (DK) 2024-01-02 — — US disclosed
EP-4269684-A2 ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES Novozymes A/S (DK) 2023-11-01 — — EP disclosed
EP-4219702-A2 ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME Novozymes A/S (DK) 2023-08-02 — — EP disclosed
CN-109312319-B Variant polypeptides with improved properties and uses thereof 诺维信公司 2023-05-16 — — CN disclosed
US-11248193-B2 Stabilized alpha-amylase variants and use of the same NOVOZYMES A/S (DK) 2022-02-15 — — US disclosed
EP-1361274-A1 POLYPEPTIDE HAVING ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE ACTIVITY Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-11-12 — — EP disclosed
EP-1360988-A1 DEHYDRATING AGENT AND METHOD FOR DEHYDRATING MOIST ARTICLE USING THE AGENT AND DEHYDRATED ARTICLE OBTAINED BY THE METHOD Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-11-12 — — EP disclosed
US-20030194762-A1 Alpha-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2003-10-16 — — US disclosed
EP-1335020-A1 POLYPEPTIDES HAVING ALPHA-ISOMALTOSYL TRANSFERASE ACTIVITY Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-08-13 — — EP disclosed
EP-1326965-A2 ALPHA-AMYLASE VARIANT WITH ALTERED PROPERTIES Novozymes A/S (DK) 2003-07-16 — — EP disclosed
WO-2002092797-A2 ALPHA-AMYLASE VARIANT WITH ALTERED PROPERTIES NOVOZYMES A/S (DK) 2002-11-21 — — WO disclosed
EP-1229112-A1 ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2002-08-07 — — EP disclosed
WO-2002031124-A2 ALPHA-AMYLASE VARIANT WITH ALTERED PROPERTIES NOVOZYMES A/S (DK) 2002-04-18 — — WO disclosed
JP-S6346201-A MULTIPLY BRANCHED CYCLODEXTRIN AND ITS PRODUCTION NATL FOOD RES INST 1988-02-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040121431-A1 used for formation of cyclotetrasaccharide from a saccharide with a glucose polymerization degree of 3 or higher; genetic engineering UGGT1, IDUA, GALE LGALS8 1327/4885LGALS3 1725/4885LGALS4 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback