⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624457 | 0.89 | — | — | |
| SCHEMBL28412386 | 0.84 | — | — | |
| SCHEMBL12828010 | 0.78 | — | — | |
| SCHEMBL4368259 | 0.76 | — | — | |
| SCHEMBL23529565 | 0.75 | — | — | |
| SCHEMBL11643044 | 0.75 | — | — | |
| SCHEMBL4430036 | 0.75 | — | — | |
| SCHEMBL11643042 | 0.75 | — | — | |
| SCHEMBL294858 | 0.75 | — | — | |
| SCHEMBL4430034 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-9856340-B2 | Photocurable fluorinated polymer composition | ASAHI GLASS COMPANY, LIMITED (JP) | 2018-01-02 | — | — | US | disclosed |
| CN-105541849-A | 6-cycloalkyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as PDE9A inhibitors | BOEHRINGER INGELHEIM INT | 2016-05-04 | — | — | CN | disclosed |
| CN-103896921-B | As compound and the composition of kinases inhibitor | IRM LLC (BM) | 2016-02-24 | — | — | CN | disclosed |
| CN-103052639-B | 6-cycloalkyl-1, 5-dihydro-pyrazolo [3,4-d ] pyrimidin-4-one derivatives and their use as PDE9A inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-17 | — | — | CN | disclosed |
| CN-105143220-A | Novel pyrazole derivatives | HOFFMANN LA ROCHE | 2015-12-09 | — | — | CN | disclosed |
| EP-2468816-B1 | PHOTOCURABLE FLUORINATED POLYMER COMPOSITION | ASAHI GLASS CO LTD (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8796193-B2 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8399479-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-03-19 | — | — | US | disclosed |
| US-8394828-B2 | Quinoline-derived amide modulators of vanilloid VR1 receptor | JANSSEN PHARMACEUTICA, NV (BE) | 2013-03-12 | — | — | US | disclosed |
| US-6258507-B1 | UNSATURATED AROMATIC ACRYLATED ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-1051381-A1 | PROCESS FOR PREPARING HYDROFLUOROETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| US-6023002-A | REACTION OF A FLUORINATED ALKOXIDE WITH AN ALKYL FLUOROVINYLALKYL ETHER, THE ALKYL FLUOROVINYLALKYL ETHER HAVING ALPHA-BETA CARBON-CARBON UNSATURATION RELATIVE TO THE ETHER OXYGEN | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0955563-A1 | A photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-11-10 | — | — | EP | disclosed |
| EP-0945764-A2 | Photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-29 | — | — | EP | disclosed |
| WO-1999037598-A1 | PROCESS FOR PREPARING HYDROFLUOROETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-29 | — | — | WO | disclosed |
| EP-0648769-A1 | 12-Hetero-substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizium salts and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5380729-A | Treatment or prevention of neurodegenerative disorders or neurotoxic injuries | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| US-4403098-A | OXIDATION | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
| US-4022804-A | ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |