⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733468 | 0.82 | — | — | |
| SCHEMBL19733637 | 0.80 | MGLL (0.31) | — | |
| SCHEMBL19733465 | 0.73 | HPGD (0.32) | — | |
| SCHEMBL21137508 | 0.71 | — | — | |
| SCHEMBL26212138 | 0.71 | — | — | |
| SCHEMBL19733633 | 0.70 | — | — | |
| SCHEMBL16724697 | 0.70 | MGLL (0.35) | — | |
| SCHEMBL16330516 | 0.70 | HSD11B1 (0.41) | — | |
| SCHEMBL29825364 | 0.70 | AKT1 (0.35) | — | |
| SCHEMBL29635321 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234212-B2 | Peptide conjugates of microtubule-targeting agents as therapeutics | Cybrexa 3, Inc. (US) | 2025-02-25 | — | — | US | disclosed |
| US-20240067616-A1 | PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS | Cybrexa 3, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-11555019-B2 | Peptide conjugates of microtubule-targeting agents as therapeutics | Cybrexa 3, Inc. (US) | 2023-01-17 | — | — | US | disclosed |
| WO-2022155172-A1 | PEPTIDE CONJUGATES OF THERAPEUTICS | Cybrexa 3, Inc. (US) | 2022-07-21 | — | — | WO | disclosed |
| EP-3996749-A1 | PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS | Cybrexa 3, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| CN-114302744-A | Peptide conjugates of microtubule targeting agents as therapeutic agents | 赛博克萨3公司 | 2022-04-08 | — | — | CN | disclosed |