Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | USP1 | O94782 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775955 | 1.00 | NPC1 (0.34) | NPC1RAB9APTGS2KCNQ3KCNQ2 | |
| SCHEMBL19993247 | 0.85 | HTR6 (0.35) | NPC1RAB9APTGS2CA12CA9 | |
| SCHEMBL22775960 | 0.85 | KCNQ3 (0.40) | NPC1RAB9APTGS2KCNQ3KCNQ2 | |
| SCHEMBL29525744 | 0.84 | ATR (0.35) | PTGS2 | |
| SCHEMBL22775838 | 0.84 | HPGD (0.35) | NPC1RAB9ACA12CA9 | |
| SCHEMBL29525530 | 0.84 | HPGD (0.35) | NPC1RAB9ACA12CA9 | |
| SCHEMBL28684959 | 0.83 | PTGS2 (0.34) | NPC1RAB9APTGS2USP1 | |
| SCHEMBL22775915 | 0.82 | POLB (0.41) | RAB9APTGS2KCNQ3KCNQ2 | |
| SCHEMBL22776126 | 0.82 | HTR6 (0.32) | KCNQ3KCNQ2HTR6 | |
| SCHEMBL29525651 | 0.82 | HTR6 (0.32) | KCNQ3KCNQ2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983411-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI Industries Ltd. (IN) | 2022-04-20 | — | — | EP | claimed |
| EP-3983411-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI Industries Ltd. (IN) | 2022-04-20 | — | — | EP | disclosed |