Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | KDR | P35968 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067101 | 0.77 | PIK3CD (0.42) | ALDH1A1TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL29527107 | 0.76 | AAK1 (0.49) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL21500091 | 0.76 | AAK1 (0.49) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL187591 | 0.72 | CNR2 (0.42) | LMNACYP1A2CYP2C19SMN1; SMN2CNR2 | |
| SCHEMBL1771736 | 0.72 | MEN1 (0.38) | LMNAKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11659268 | 0.72 | ALDH1A1 (0.80) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL31287064 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRNPSR1HPGDKDM4E | |
| SCHEMBL16696397 | 0.71 | SMN1; SMN2 (0.56) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL31078996 | 0.71 | SMN1; SMN2 (0.56) | L3MBTL1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL7407182 | 0.70 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1TSHRLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240730-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099044-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |