Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400441 | 1.00 | NOTUM (0.55) | NOTUMLMNAMEN1KMT2AKDM4E | |
| SCHEMBL2825430 | 0.93 | NOTUM (0.62) | NOTUMLMNAMEN1KMT2AKDM4E | |
| SCHEMBL29453088 | 0.93 | NOTUM (0.62) | NOTUMLMNAMEN1KMT2AKDM4E | |
| SCHEMBL184614 | 0.84 | NOTUM (0.67) | NOTUMLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1401499 | 0.84 | CA1 (0.58) | NOTUMLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26334404 | 0.81 | NOTUM (0.53) | NOTUMLMNAKDM4EMAPTCA12 | |
| SCHEMBL521670 | 0.80 | CA1 (0.58) | NOTUMLMNAMEN1KMT2AKDM4E | |
| Methyl 3,5-Dibromobenzoate SCHEMBL2408987 | 0.80 | NOTUM (0.67) | NOTUMLMNAKDM4EMAPTCA12 | |
| SCHEMBL22400351 | 0.80 | NOTUM (0.88) | NOTUMLMNAKDM4EMAPTCA12 | |
| SCHEMBL22400347 | 0.80 | NOTUM (0.51) | NOTUMLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946363-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2022-02-09 | — | — | EP | disclosed |