Sugi Predict

Sugi Predict / Compounds / SCHEMBL22400441

SCHEMBL22400441

SCHEMBL22400441

COC(=O)c1cc(Br)cc(C(=O)c2cc(F)cc(Br)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOTUM Q6P988 2/20 0.55
▸ LMNA P02545 3/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ KDM4E B2RXH2 5/20 0.45
▸ MAPT P10636 3/20 0.43
▸ CA12 O43570 1/20 0.43
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ CA7 P43166 1/20 0.43
▸ CA9 Q16790 1/20 0.43
▸ CA14 Q9ULX7 1/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.42
▸ POLB P06746 3/20 0.42
▸ GAA P10253 1/20 0.42
▸ NFKB1 P19838 1/20 0.42
▸ XDH P47989 1/20 0.42
▸ GFER P55789 1/20 0.42
▸ NFKB2 Q00653 1/20 0.42
▸ RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29528596 1.00 NOTUM (0.55) NOTUMLMNAMEN1KMT2AKDM4E
SCHEMBL2825430 0.93 NOTUM (0.62) NOTUMLMNAMEN1KMT2AKDM4E
SCHEMBL29453088 0.93 NOTUM (0.62) NOTUMLMNAMEN1KMT2AKDM4E
SCHEMBL184614 0.84 NOTUM (0.67) NOTUMLMNAMEN1KMT2AKDM4E
SCHEMBL1401499 0.84 CA1 (0.58) NOTUMLMNAMEN1KMT2AKDM4E
SCHEMBL26334404 0.81 NOTUM (0.53) NOTUMLMNAKDM4EMAPTCA12
SCHEMBL521670 0.80 CA1 (0.58) NOTUMLMNAMEN1KMT2AKDM4E
Methyl 3,5-Dibromobenzoate SCHEMBL2408987 0.80 NOTUM (0.67) NOTUMLMNAKDM4EMAPTCA12
SCHEMBL22400351 0.80 NOTUM (0.88) NOTUMLMNAKDM4EMAPTCA12
SCHEMBL22400347 0.80 NOTUM (0.51) NOTUMLMNAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122226-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2025-04-17 — — US disclosed
US-12227528-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2025-02-18 — — US disclosed
CN-117624207-A Glucose-sensitive albumin binding derivatives 诺和诺德股份有限公司 2024-03-01 — — CN disclosed
CN-111315751-B Glucose-sensitive albumin binding derivatives 诺和诺德股份有限公司 2023-12-12 — — CN disclosed
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-10-19 — — US disclosed
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-10-19 — — US disclosed
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-10-19 — — US disclosed
US-11767332-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2023-09-26 — — US disclosed
US-11767332-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2023-09-26 — — US disclosed
US-11767332-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2023-09-26 — — US disclosed
EP-3707145-B1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2023-06-21 — — EP disclosed
US-20220184184-A1 GLUCOSE SENSITIVE INSULIN DERIVATIVES NOVO NORDISK A/S (DK) 2022-06-16 — — US disclosed
US-20220081451-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2022-03-17 — — US disclosed
EP-3946363-A2 GLUCOSE SENSITIVE INSULIN DERIVATIVES Novo Nordisk A/S (DK) 2022-02-09 — — EP disclosed
US-11186595-B2 Glucose-sensitive albumin-binding derivatives NOVO NORDISK A/S (DK) 2021-11-30 — — US disclosed
CN-113646329-A Glucose-sensitive insulin derivatives 诺和诺德股份有限公司 2021-11-12 — — CN disclosed
US-20200325160-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK A/S (DK) 2020-10-15 — — US disclosed
WO-2020201041-A2 GLUCOSE SENSITIVE INSULIN DERIVATIVES NOVO NORDISK A/S (DK) 2020-10-08 — — WO disclosed
EP-3707145-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES Novo Nordisk A/S (DK) 2020-09-16 — — EP disclosed
CN-111315751-A Glucose-sensitive albumin binding derivatives 诺沃挪第克公司 2020-06-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220184184-A1 GLUCOSE SENSITIVE INSULIN DERIVATIVES IAPP, IRS1, GPR119 NOTUM 2630/4885LMNA 4159/4885MEN1 2588/4885
US-12227528-B2 Glucose-sensitive albumin-binding derivatives ALB, DBI, FABP4 NOTUM 2218/4885LMNA 4627/4885MEN1 4135/4885
US-20230331745-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 NOTUM 2218/4885LMNA 4627/4885MEN1 4135/4885
US-11767332-B2 Glucose-sensitive albumin-binding derivatives ALB, DBI, FABP4 NOTUM 2218/4885LMNA 4627/4885MEN1 4135/4885
US-20220081451-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 NOTUM 2218/4885LMNA 4627/4885MEN1 4135/4885
US-20250122226-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 NOTUM 2218/4885LMNA 4627/4885MEN1 4135/4885
US-11186595-B2 Glucose-sensitive albumin-binding derivatives ALB, GPR119, MLX NOTUM 3555/4885LMNA 4214/4885MEN1 1637/4885
US-20200325160-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, GPR119, MLX NOTUM 3555/4885LMNA 4214/4885MEN1 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.