Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.67 |
| ▸ | CDK2 | P24941 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527706 | 0.94 | KMT2A (0.66) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29528289 | 0.89 | KDM4E (0.66) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29528408 | 0.87 | RAB9A (0.76) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL8969803 | 0.87 | KMT2A (0.76) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29528283 | 0.85 | ALDH1A1 (0.66) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL11252112 | 0.85 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29527718 | 0.85 | KDM4E (0.69) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29528162 | 0.85 | RAB9A (0.76) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL11160288 | 0.82 | KDM4E (0.82) | KMT2AMEN1RAB9ANPC1CCNE1 | |
| SCHEMBL29528054 | 0.82 | KDM4E (0.57) | KMT2AMEN1RAB9ANPC1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248438-B | Pyrazole compound and preparation method thereof | 浙大城市学院 | 2022-04-12 | — | — | CN | disclosed |