Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330056 | 1.00 | ABHD6 (0.60) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL29528794 | 0.89 | ESR2 (0.74) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL587847 | 0.89 | ESR2 (0.74) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL29587073 | 0.89 | NR1H2 (0.72) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL1011003 | 0.89 | NR1H2 (0.72) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| Hydrochloric Acid SCHEMBL38653092 | 0.88 | NR1H2 (0.70) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL24265586 | 0.86 | NR1H2 (0.62) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL29574152 | 0.86 | NR1H2 (0.62) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL1263385 | 0.86 | ESR2 (0.63) | ABHD6HDAC1ESR2NR1H2DDB1 | |
| SCHEMBL19657720 | 0.85 | NR1H2 (0.48) | ABHD6HDAC1ESR2NR1H2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |
| CN-118076605-A | Substituted 1H-pyrazolo [4,3-c ] quinolines, methods of preparation and uses thereof | 洛蒙治疗公司 | 2024-05-24 | — | — | CN | disclosed |