SCHEMBL29528796

SCHEMBL29528796

Cn1c(-c2ccc(-c3ccc(-c4ccccc4)c(-c4ccc(-c5nc6cccnc6n5C)cc4)c3-c3ccc(-c4nc5cccnc5n4C)cc3)cc2)nc2cccnc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
ATM Q13315 1/20 0.43
BRD4 O60885 2/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CCNB2 O95067 1/20 0.41
CDK1 P06493 1/20 0.41
CCNB1 P14635 1/20 0.41
CDK5 Q00535 1/20 0.41
CDK5R1 Q15078 1/20 0.41
CCNB3 Q8WWL7 1/20 0.41
DHODH Q02127 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9611679 0.89 MAPT (0.52) KDM4EMAPTATMBRD4MEN1
SCHEMBL29528775 0.88 KDM4E (0.44) KDM4EMAPTATMBRD4MEN1
SCHEMBL29528745 0.88 KDM4E (0.44) KDM4EMAPTATMBRD4MEN1
SCHEMBL29528491 0.87 KDM4E (0.43) KDM4EMAPTATMBRD4MEN1
SCHEMBL29529481 0.84 MAPT (0.39) KDM4EMAPTATMBRD4MEN1
SCHEMBL29528496 0.79 KDM4E (0.39) KDM4EMAPTATMBRD4MEN1
SCHEMBL12970201 0.79 KDM4E (0.52) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL9975957 0.79 KDM4E (0.49) KDM4EMAPTBRD4MEN1KMT2A
SCHEMBL29529047 0.78 MAPT (0.42) KDM4EMAPTATMBRD4MEN1
SCHEMBL12970523 0.78 KDM4E (0.46) KDM4EMAPTBRD4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11283027-B1 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11283027-B1 Composition of matter for use in organic light-emitting diodes ALDH1A2, CYBA, CRY2 KDM4E 4331/4885MAPT 214/4885ATM 2385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.