Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 6/20 | 0.61 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400474 | 1.00 | CFTR (0.61) | CFTRSOS1NOTUMMAPTLDHA | |
| SCHEMBL23754415 | 0.84 | CFTR (0.61) | CFTRSOS1NOTUMMAPTPDK2 | |
| SCHEMBL15797511 | 0.83 | CFTR (0.78) | CFTRSOS1NOTUMMAPT | |
| SCHEMBL19491469 | 0.82 | CFTR (0.48) | CFTRSOS1NOTUMMAPTMBOAT4 | |
| SCHEMBL22400408 | 0.81 | ASPH (0.45) | CFTRNOTUMMAPT | |
| SCHEMBL29529025 | 0.81 | ASPH (0.45) | CFTRNOTUMMAPT | |
| SCHEMBL26334537 | 0.81 | CFTR (0.58) | CFTRSOS1NOTUMMAPTLDHA | |
| SCHEMBL2425745 | 0.79 | CFTR (0.68) | CFTRSOS1NOTUMMAPT | |
| SCHEMBL1920431 | 0.79 | CFTR (0.46) | CFTRSOS1MAPTNR4A2PDK2 | |
| SCHEMBL30280800 | 0.79 | CFTR (0.46) | CFTRSOS1MAPTNR4A2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946363-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2022-02-09 | — | — | EP | disclosed |