Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13447331 | 0.90 | IKBKB (0.43) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL29686211 | 0.87 | PLA2G4A (0.44) | ALDH1A1MEN1KMT2APLA2G4AIKBKB | |
| SCHEMBL17717276 | 0.85 | KMT2A (0.44) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL2877357 | 0.84 | PLA2G4A (0.43) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL13412495 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL17977280 | 0.82 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL4071597 | 0.81 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL4911470 | 0.79 | KMT2A (0.39) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 | |
| SCHEMBL2218602 | 0.79 | KMT2A (0.38) | ALDH1A1MEN1KMT2ATP53KDM4E | |
| SCHEMBL5875662 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2AHSD17B10GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |