SCHEMBL29529656

SCHEMBL29529656

CC(C)(C)OC(=O)[C@H](Cc1cncc(C#N)c1)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.44
TP53 P04637 2/20 0.44
CD274 Q9NZQ7 1/20 0.43
ABCB1 P08183 2/20 0.42
MDM2 Q00987 1/20 0.42
CTSS P25774 2/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30638165 0.91 MDM4 (0.43) MDM4TP53CD274ABCB1MDM2
SCHEMBL27273417 0.91 MDM4 (0.43) MDM4TP53CD274ABCB1MDM2
SCHEMBL21639029 0.88 MDM4 (0.50) MDM4TP53CD274MDM2
SCHEMBL29529296 0.88 MDM4 (0.50) MDM4TP53CD274MDM2
SCHEMBL21639033 0.88 MDM4 (0.50) MDM4TP53CD274MDM2
SCHEMBL25657536 0.88 MDM4 (0.46) MDM4TP53MDM2PTPN1
SCHEMBL29633938 0.87 MDM4 (0.47) MDM4TP53MDM2
SCHEMBL29529053 0.86 MDM4 (0.46) MDM4TP53MDM2CTSSCTSL
SCHEMBL28741541 0.86 MDM4 (0.49) MDM4TP53MDM2
SCHEMBL29529279 0.85 CTSB (0.43) MDM4TP53ABCB1MDM2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604326-B1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORP (JP) 2026-01-07 EP disclosed
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 MDM4 4154/4885TP53 1409/4885CD274 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.