SCHEMBL29530673

SCHEMBL29530673

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
GNPAT O15228 1/20 0.40
GSR P00390 1/20 0.40
CPB2 Q96IY4 2/20 0.39
FURIN P09958 3/20 0.39
NMT2 O60551 1/20 0.39
NMT1 P30419 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30390475 0.91 PDCD1LG2 (0.47) PDCD1LG2CD274FURIN
SCHEMBL38657332 0.91 GSR (0.46) GSRCPB2FURINNMT2NMT1
SCHEMBL30578972 0.90 GNPAT (0.41) FOLH1PDCD1LG2CD274GNPATFURIN
SCHEMBL29477124 0.89 FOLH1 (0.49) FOLH1PDCD1LG2CD274CPB2FURIN
SCHEMBL30974486 0.89 ERAP2 (0.43)
SCHEMBL29367178 0.89 NMT1 (0.44) FOLH1NMT2NMT1
SCHEMBL29530917 0.88 GNPAT (0.43) FOLH1PDCD1LG2CD274GNPAT
SCHEMBL29531241 0.87 NMT2 (0.42) FOLH1GSRCPB2FURINNMT2
SCHEMBL29367039 0.87 NMT2 (0.43) FOLH1GNPATNMT2NMT1
SCHEMBL29460689 0.86 FOLH1 (0.49) FOLH1PDCD1LG2CD274GSRFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312390-B2 Rapid-acting insulin analogues of enhanced stability CASE WESTERN RESERVE UNIVERSITY (US) 2025-05-27 US disclosed
US-20220112262-A1 RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY CASE WESTERN RESERVE UNIVERSITY 2022-04-14 US disclosed