Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | SLC6A7 | Q99884 | 9/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880929 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL29531076 | 0.81 | POLB (0.63) | ALDH1A1HPGDSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL12312321 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL520418 | 0.81 | POLB (0.63) | ALDH1A1HPGDSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL30870987 | 0.81 | HPGD (0.64) | ALDH1A1HPGDHSD17B10L3MBTL1TSHR | |
| SCHEMBL15651739 | 0.81 | HPGD (0.60) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL30871381 | 0.81 | HPGD (0.60) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL1782181 | 0.81 | HPGD (0.64) | ALDH1A1HPGDHSD17B10L3MBTL1TSHR | |
| SCHEMBL4418409 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ESLC6A7LMNA | |
| SCHEMBL4314298 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ESLC6A7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478539-B | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |