SCHEMBL29530892

SCHEMBL29530892

C[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 9/20 0.46
▸ KDM1A O60341 1/20 0.39
▸ NMT2 O60551 1/20 0.38
▸ NMT1 P30419 1/20 0.38
▸ SIRT2 Q8IXJ6 1/20 0.37
▸ SIRT5 Q9NXA8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530913 0.91 FURIN (0.43) FURINNMT2NMT1
SCHEMBL31396831 0.90 FURIN (0.42) FURIN
SCHEMBL29530917 0.89 GNPAT (0.43) —
SCHEMBL29530901 0.89 FOLH1 (0.51) FURINNMT2NMT1
SCHEMBL29782532 0.89 CPB2 (0.41) FURINNMT2NMT1
SCHEMBL31720968 0.89 CPB2 (0.41) FURINNMT2NMT1
SCHEMBL29630669 0.88 FURIN (0.47) FURINNMT2NMT1SIRT2SIRT5
SCHEMBL31474489 0.87 FOLH1 (0.42) FURIN
SCHEMBL30567426 0.87 FOLH1 (0.42) FURIN
SCHEMBL29531241 0.86 NMT2 (0.42) FURINNMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312390-B2 Rapid-acting insulin analogues of enhanced stability CASE WESTERN RESERVE UNIVERSITY (US) 2025-05-27 — — US disclosed
US-20220112262-A1 RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY CASE WESTERN RESERVE UNIVERSITY 2022-04-14 — — US disclosed
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