Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600367 | 1.00 | F2 (0.51) | F2OPRM1OPRK1OPRD1EPHA2 | |
| SCHEMBL11358432 | 0.95 | F2 (0.48) | F2OPRM1OPRK1OPRD1EPHA2 | |
| 4-Nitroaniline SCHEMBL27635238 | 0.89 | OPRM1 (0.46) | F2OPRM1OPRK1OPRD1EPHA2 | |
| SCHEMBL30693083 | 0.88 | F2 (0.58) | F2OPRM1OPRK1OPRD1EPHA2 | |
| SCHEMBL11338965 | 0.87 | OPRM1 (0.49) | OPRM1OPRK1OPRD1EPHA2NMUR2 | |
| SCHEMBL27635235 | 0.87 | OPRM1 (0.46) | F2OPRM1OPRK1OPRD1EPHA2 | |
| Hydrochloric Acid SCHEMBL11328634 | 0.86 | OPRM1 (0.49) | OPRM1OPRK1OPRD1EPHA2NMUR2 | |
| SCHEMBL5704652 | 0.86 | FKBP4 (0.48) | OPRM1OPRK1OPRD1 | |
| SCHEMBL29934589 | 0.86 | OPRM1 (0.58) | F2OPRM1OPRK1OPRD1EPHA2 | |
| SCHEMBL30782709 | 0.86 | OPRM1 (0.62) | F2OPRM1OPRK1OPRD1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827539-A2 | KUNITZ TYPE PROTEASE INHIBITORS | SCIOS INC. (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996035788-A2 | KUNITZ TYPE PROTEASE INHIBITORS | SCIOS, INC. (US) | 1996-11-14 | — | — | WO | disclosed |
| US-4372941-A | FOR PRESENCE OF HYDROLYTIC ENZYMES | UNIVERSITY OF MIAMI | 1983-02-08 | — | — | US | disclosed |
| US-4115374-A | IODO-P-HYDROXYPHENYL-GLYCYLGLYCINE | RYAN JAMES WALTER | 1978-09-19 | — | — | US | disclosed |