Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 16/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18836478 | 1.00 | EIF4A1 (0.49) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL17414041 | 1.00 | EIF4A1 (0.49) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL18862683 | 0.89 | EIF4A1 (0.46) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL18862696 | 0.83 | EIF4A1 (0.41) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL17396636 | 0.82 | ABHD10 (0.57) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL17396638 | 0.82 | ABHD10 (0.57) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL21852385 | 0.78 | ABHD10 (0.53) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL21852401 | 0.77 | ABHD10 (0.56) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL21852364 | 0.77 | ABHD10 (0.53) | EIF4A1CYP3A4HIF1AABHD10NFKB1 | |
| SCHEMBL21852374 | 0.77 | ABHD10 (0.53) | EIF4A1CYP3A4HIF1AABHD10NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998257-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2022-05-18 | — | — | EP | disclosed |