Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | NPY4R | P50391 | 5/20 | 0.36 |
| ▸ | NPY1R | P25929 | 4/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019315 | 0.99 | PRCP (0.41) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL30416888 | 0.95 | MAPK8 (0.42) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL29947814 | 0.92 | PRCP (0.44) | PRCPDPP7MEN1KMT2AGHSR | |
| SCHEMBL29496543 | 0.91 | MEN1 (0.44) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL6520003 | 0.90 | MAPK8 (0.45) | MAPK8MAPK9MAPK10NPY5RNPY4R | |
| SCHEMBL31720924 | 0.90 | PRCP (0.41) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL29531541 | 0.90 | PRCP (0.41) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL30844263 | 0.90 | KDM1A (0.45) | MAPK8MAPK9MAPK10GHSRKDM1A | |
| SCHEMBL30686002 | 0.89 | MAPK8 (0.42) | PRCPDPP7MEN1KMT2AMAPK8 | |
| SCHEMBL29437943 | 0.89 | MAPK8 (0.43) | PRCPMEN1KMT2AMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |