SCHEMBL29947814

SCHEMBL29947814

C[C@H](NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 3/20 0.44
▸ DPP7 Q9UHL4 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GHSR Q92847 1/20 0.37
▸ CTSC P53634 1/20 0.35
▸ REN P00797 1/20 0.35
▸ HDAC3 O15379 5/20 0.35
▸ HDAC1 Q13547 5/20 0.35
▸ HDAC2 Q92769 5/20 0.35
▸ HDAC10 Q969S8 5/20 0.35
▸ HDAC11 Q96DB2 5/20 0.35
▸ HDAC8 Q9BY41 5/20 0.35
▸ HDAC6 Q9UBN7 5/20 0.35
▸ CALCRL Q16602 1/20 0.35
▸ NCOR2 Q9Y618 1/20 0.35
▸ TLR2 O60603 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531712 0.92 PRCP (0.42) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL31019315 0.91 PRCP (0.41) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL30193521 0.90 MEN1 (0.45) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL29947667 0.89 EED (0.41) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL31572023 0.88 MEN1 (0.48) PRCPDPP7MEN1KMT2ACTSC
SCHEMBL30193454 0.87 PRCP (0.44) PRCPDPP7MEN1KMT2ACALCRL
SCHEMBL30416888 0.87 MAPK8 (0.42) PRCPDPP7MEN1KMT2ACALCRL
SCHEMBL29531751 0.86 DPP7 (0.45) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL30713450 0.86 DPP7 (0.45) PRCPDPP7MEN1KMT2AGHSR
SCHEMBL30193219 0.85 MEN1 (0.42) PRCPDPP7MEN1KMT2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP claimed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US claimed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP disclosed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US disclosed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP disclosed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES TLR7, TLR8, TLR9 PRCP 1840/4885DPP7 1361/4885MEN1 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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