Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306171 | 1.00 | CYP1A2 (0.43) | CYP1A2SMN1; SMN2GAATDP1PAX8 | |
| SCHEMBL6174042 | 0.80 | PDE10A (0.39) | CYP1A2SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL2773204 | 0.80 | TDP1 (0.54) | SMN1; SMN2GAATDP1PAX8MEN1 | |
| Hydrochloric Acid SCHEMBL27643164 | 0.78 | TDP1 (0.52) | SMN1; SMN2GAATDP1PAX8MEN1 | |
| SCHEMBL29401720 | 0.78 | TDP1 (0.52) | SMN1; SMN2GAATDP1PAX8MEN1 | |
| SCHEMBL27961656 | 0.77 | PDE10A (0.37) | CYP1A2SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL28150861 | 0.77 | TSHR (0.43) | SMN1; SMN2GAATDP1PAX8MEN1 | |
| SCHEMBL1121873 | 0.77 | GPR35 (0.50) | SMN1; SMN2GAATDP1PAX8MEN1 | |
| SCHEMBL25330812 | 0.77 | TDP1 (0.50) | CYP1A2SMN1; SMN2GAATDP1PAX8 | |
| SCHEMBL5217925 | 0.74 | MAOA (0.42) | SMN1; SMN2TDP1PAX8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380738-A | Synthetic method of 3-bromo-4-chloro-2-methylpyridine | 都创(重庆)医药科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-114380738-A | Synthetic method of 3-bromo-4-chloro-2-methylpyridine | 都创(重庆)医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |